| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596456 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
An active compound having antitumor activity was isolated from the root of Anthriscus sylvestris. Flow cytometric analysis showed that it arrests the cell cycle in the G2/M phase prior to apoptosis. Its mechanisms of action involve inhibition of tubulin polymerization, dysregulation of cyclin A and cyclin B1 expression, and activation of caspases-3 and -7.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Yeonjoong Yong, Soon Young Shin, Young Han Lee, Yoongho Lim,