| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596481 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
The anticancer activities of alkyl esters and NO-donors of ferulic acid (FA) and caffeic acid (CA) were assessed by a high-throughout screening (HTS) method, and the structure-activity relationships were described. CA alkyl esters had better anticancer activities than FA alkyl esters with the same alkyl substituent. Mono-nitrates and phenylfuroxan nitrates were more potent than the dual nitrates. Phenylsulfonylfuroxan nitrates of FA, especially compounds 8b-8d, exhibited more potent activities in anticancer.
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Authors
Weixia Li, Nianguang Li, Yuping Tang, Baoquan Li, Li Liu, Xu Zhang, Haian Fu, Jin-ao Duan,