Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596486 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
The design, synthesis and activity of a macrocyclic phosphino dipeptide isostere inhibitor of BACE1 with improved human serum stability are reported.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Timo Huber, Florian Manzenrieder, Christian A. Kuttruff, Cornelia Dorner-Ciossek, Horst Kessler,