| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596495 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
The compounds show cytotoxic activity against multidrug resistant LoVo/DX, MES-SA/DX5 and HL-60 sublines, induce the G2M phase cell cycle arrest in Jurkat cells, and inhibit topoisomerase II activity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors](/preview/png/10596495.png "First Page Preview: New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors")
Authors
Wojciech Luniewski, Joanna Wietrzyk, Joanna Godlewska, Marta Switalska, Malgorzata Piskozub, Wanda Peczynska-Czoch, Lukasz Kaczmarek,