Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596502 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
The separated enantiomers of three PPAPs, including nemorosone, clusianone, and an unnatural 'Type C' derivative, have been screened for activity against HeLa (cervix carcinoma), MIA-PaCa-2 (pancreatic carcinoma), and MCF7 (mamma carcinoma) cancer cell lines. All of the isomers examined gave surprisingly similar results in the screens.
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Authors
Nigel S. Simpkins, Frank Holtrup, Vincent Rodeschini, James D. Taylor, Robert Wolf,