| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596516 | Bioorganic & Medicinal Chemistry Letters | 2012 | 7 Pages |
Abstract
Benzothiazole amides were identified as TRPV1 antagonists from high throughput screening. Compound 37 maintained potent antagonism with improved metabolic stability and was shown to be active in rat models of pain.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yevgeni Besidski, William Brown, Johan Bylund, Michael Dabrowski, Sophie Dautrey, Magali Harter, Lucy Horoszok, Yin Hu, Dean Johnson, Shawn Johnstone, Paul Jones, Sandrine Leclerc, Karin Kolmodin, Inger Kers, Maryse Labarre, Denis Labrecque,