| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596578 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
We report the synthesis of Arg-Gln-Trp-Arg-Arg-Trp-Trp-Gln-Arg-NH2 attached to the 4-N-carboxybutyl-5-fluorocytosine residue at the N-terminus of the peptide via peptide bond formation is reported. This compound exhibited a significant cytotoxic activity against a culture of HepG2 cells.
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Authors
Csaba Somlai, Estela Correche, Monica Olivella, Laia Tolosa, Maria José Gomez Lechon, György Dombi, Gábor K. Tóth, Botond Penke, Ricardo D. Enriz,