| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596621 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
6â³-Triazole-substituted-α-galactosyl ceramides 12a-f, 13, 14 and 15 have been synthesised. Along with azide precursor 11, their ability to activate iNKT cells and stimulate the production of IL-2 cytokines in vitro, and IFN-γ and IL-4 cytokines in vivo, has been evaluated.
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Authors
Peter J. Jervis, Lisa M. Graham, Erin L. Foster, Liam R. Cox, Steven A. Porcelli, Gurdyal S. Besra,