Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596673 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
Over the past few years a number of components of the PI3K/mTOR pathway have been the subject of intense drug discovery activities both in pharmaceutical companies and in academia. This review article summarizes progress made in the identification and development of allosteric and ATP-competitive kinase inhibitors of mTOR and their potential therapeutic use in oncology.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Carlos GarcÃa-EcheverrÃa,