Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596704 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Synthesis and broad-spectrum anticancer activity of a novel heterocyclic compound 1 containing the title imidazo[4,5-e][1,3]diazepine ring system have been reported. The compound shows potent in vitro antitumor activity with low micromolar IC50's against prostate, lung, breast, and ovarian cancer cell lines tested.
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Organic Chemistry
Authors
Min Xie, Ravi K. Ujjinamatada, Mariola Sadowska, Rena G. Lapidus, Martin J. Edelman, Ramachandra S. Hosmane,