| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596704 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Synthesis and broad-spectrum anticancer activity of a novel heterocyclic compound 1 containing the title imidazo[4,5-e][1,3]diazepine ring system have been reported. The compound shows potent in vitro antitumor activity with low micromolar IC50's against prostate, lung, breast, and ovarian cancer cell lines tested.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![A novel, broad-spectrum anticancer compound containing the imidazo[4,5-e][1,3]diazepine ring system](/preview/png/10596704.png "First Page Preview: A novel, broad-spectrum anticancer compound containing the imidazo[4,5-e][1,3]diazepine ring system")
Authors
Min Xie, Ravi K. Ujjinamatada, Mariola Sadowska, Rena G. Lapidus, Martin J. Edelman, Ramachandra S. Hosmane,