| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596748 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
The synthesis of the urea derivatives were performed rapidly in a one-pot manner using a manual synthesizer. Several compounds containing hydrophobic substituents at R1 and R2 showed potent inhibitory activities against TNF-α production.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hiroshi Enomoto, Ayako Sawa, Hiroshi Suhara, Noriyoshi Yamamoto, Hiroyuki Inoue, Chikako Setoguchi, Fumio Tsuji, Masahiro Okamoto, Yoshimasa Sasabuchi, Masato Horiuchi, Masakazu Ban,