| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596800 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
SAR studies led to the discovery of tetralin allylic amines as potent and selective bradykinin B1 receptor antagonists (hB1 IC50Â =Â 1.3Â nM for compound 16).
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Qingyian Liu, Wenyuan Qian, Aiwen Li, Kaustav Biswas, Jian Jeffrey Chen, Christopher Fotsch, Nianhe Han, Chester Yuan, Leyla Arik, Gloria Biddlecome, Eileen Johnson, Gondi Kumar, Dianna Lester-Zeiner, Gordon Y. Ng, Randall W. Hungate, Benny C. Askew,