Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596831 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Fifty-six 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives were synthesized and developed as potent inhibitors of FabH. Escherichia coli FabH inhibitory assay was undertaken and the results suggested that compounds 12 and 13 were potent E. coli FabH inhibitors.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Peng-Cheng Lv, Juan Sun, Yin Luo, Ying Yang, Hai-Liang Zhu,