Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596893 | Bioorganic & Medicinal Chemistry Letters | 2005 | 6 Pages |
Abstract
Docking experiments using a number of published crystal structures of HMG-CoA reductase with the potent hypocholesterolemic agent α-asarone are described. The docking results will be valuable for the structure-based design novel hypolipidemic agents.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
José Luis Medina-Franco, Fabián López-Vallejo, Sergio RodrÃguez-Morales, Rafael Castillo, Germán Chamorro, JoaquÃn Tamariz,