Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596915 | Bioorganic & Medicinal Chemistry Letters | 2005 | 6 Pages |
Abstract
Most probable conformation in solution of rhazinilam (1) was analyzed and CoMFA results have been applied successfully to rationalize the inhibitory activities of tubulin disassembly of rhazinilam and its analogues in terms of their steric and electrostatic properties.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hiroshi Morita, Khalijah Awang, A. Hamid A. Hadi, Koichi Takeya, Hideji Itokawa, Jun'ichi Kobayashi,