| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10596945 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Sphingosine-1-phosphate (S-1P) derivatives such as threo-(2S,3S)-S-1Ps and threo-(1S,2R)-2-amino-1-aryl-3-bromopropanols have been prepared. These threo-amino alcohols have shown potent inhibitory activity against Ca2+ ion increases in HL60 cells induced by natural erythro-S-1P.
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Authors
Teiichi Murakami, Kiyotaka Furusawa, Tadakazu Tamai, Kazuyoshi Yoshikai, Masazumi Nishikawa,