Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596961 | Bioorganic & Medicinal Chemistry Letters | 2005 | 6 Pages |
Abstract
The synthesis and biological activity of a novel series of EP1 receptor antagonists is reported. SAR studies in this series led to the identification of optimized inhibitors 4, 7, and 12a.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yves Ducharme, Marc Blouin, Marie-Claude Carrière, Anne Chateauneuf, Bernard Côté, Danielle Denis, Richard Frenette, Gillian Greig, Stacia Kargman, Sonia Lamontagne, Evelyn Martins, François Nantel, Gary O'Neill, Nicole Sawyer, Kathleen M. Metters,