Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10596979 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
The mGlu5 receptor has been implicated in a number of CNS disorders. Herein, we report on the discovery, synthesis, and biological evaluation of dipyridyl amides as small molecules mGluR5 antagonists.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Céline Bonnefous, Jean-Michel Vernier, John H. Hutchinson, Janice Chung, Grace Reyes-Manalo, Theodore Kamenecka,