| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10598127 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Curcuminoids were isolated from Curcuma longa and their pyrazole and isoxazole analogues were synthesized and evaluated for antioxidant, COX-1/COX-2 inhibitory and anti-inflammatory activities. Molecular docking study revealed the binding orientations of curcumin analogues in the active sites of COX-1 and COX-2.
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Authors
C. Selvam, Sanjay M. Jachak, Ramasamy Thilagavathi, Asit. K. Chakraborti,