| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10598140 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
A series of fused pyrimidine based inhibitors of PDE7 have been derived from an earlier screening lead. The synthesis, structure-activity relationships (SAR) and selectivity against several other PDE family members are described.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
James Kempson, William J. Pitts, Joseph Barbosa, Junqing Guo, Omonike Omotoso, Andrew Watson, Karen Stebbins, Gary C. Starling, John H. Dodd, Joel C. Barrish, Raymond Felix, Karl Fischer,