Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10598142 | Bioorganic & Medicinal Chemistry Letters | 2005 | 6 Pages |
Abstract
The synthesis of novel heterocycle containing thyromimetics is reported. Potent indole thyromimetics are presented (e.g., 8) that show a 10-fold selectivity in activation of THRβ over THRα.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Helmut Haning, Michael Woltering, Ulrich Mueller, Gunter Schmidt, Carsten Schmeck, Verena Voehringer, Axel Kretschmer, Josef Pernerstorfer,