| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10598180 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
2-Anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones are inhibitors of c-Src and Wee1 kinases. Selectivity for c-Src was not markedly changed by 6-phenyl ring substituents, but was lowered by 5-alkyl substituents.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1](/preview/png/10598180.png "First Page Preview: Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1")
Authors
Brian D. Palmer, Jeff B. Smaill, Gordon W. Rewcastle, Ellen M. Dobrusin, Alan Kraker, Charles W. Moore, Randall W. Steinkampf, William A. Denny,