| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10598299 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Potent and selective TACE and MMP inhibitors utilizing the diazepine and thiazepine ring systems were synthesized and evaluated for biological activity in in vitro and in vivo models of TNF-α release and arthritis.
Related Topics
Physical Sciences and Engineering
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Authors
Arie Zask, Joshua Kaplan, XueMei Du, Gloria MacEwan, Vincent Sandanayaka, Nancy Eudy, Jeremy Levin, Guixian Jin, Jun Xu, Terri Cummons, Dauphine Barone, Semiramis Ayral-Kaloustian, Jerauld Skotnicki,