| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10598310 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
A series of [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines were designed and synthesized as CYP26 inhibitors, serving as retinoic acid metabolic blocking agents (RAMBA's).
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs)](/preview/png/10598310.png "First Page Preview: Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs)")
Authors
Mark J. Mulvihill, Julie L.C. Kan, Patricia Beck, Mark Bittner, Cara Cesario, Andrew Cooke, David M. Keane, Anthony I. Nigro, Christy Nillson, Vanessa Smith, Mary Srebernak, Feng-Lei Sun, Michael Vrkljan, Shannon L. Winski, Arlindo L. Castelhano,