| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10598353 | Bioorganic & Medicinal Chemistry Letters | 2005 | 7 Pages |
Abstract
Syntheses and SAR studies of 5-amidinobenzo[b]thiophene analogs provided compounds with low submicromolar factor IXa potency and equal or slightly better selectivity relative to factor Xa.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![5-Amidinobenzo[b]thiophenes as dual inhibitors of factors IXa and Xa](/preview/png/10598353.png "First Page Preview: 5-Amidinobenzo[b]thiophenes as dual inhibitors of factors IXa and Xa")
Authors
Jennifer X. Qiao, Xuhong Cheng, Dilip P. Modi, Karen A. Rossi, Joseph M. Luettgen, Robert M. Knabb, Prabhakar K. Jadhav, Ruth R. Wexler,