Article ID Journal Published Year Pages File Type
10598388 Bioorganic & Medicinal Chemistry Letters 2005 5 Pages PDF
Abstract
Association between RNA and DNA strands to form RNA-DNA heteroduplex is important in many biological processes. Herein, binding affinities of a 17-mer BIV Tat peptide is compared with TAR DNA duplex, RNA-DNA heteroduplex and RNA duplex. It was observed that binding affinities of Tat peptide is comparable against DNA-RNA heteroduplex and RNA duplex, whereas DNA duplex binding is decidedly poor.
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Physical Sciences and Engineering Chemistry Organic Chemistry
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