| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10598804 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
(R)-2-(4-Phenylbutyl)dihydrobenzofuran derivatives (e.g., 3 and 4) were synthesized as novel melatoninergic ligands with significantly lower vasoconstrictive activity in vitro in the rat tail artery. Binding affinity assays were performed on cloned human MT1 and MT2 receptors stably expressed in NIH3T3 cells.
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Authors
Li-Qiang Sun, Katherine Takaki, Jie Chen, Stephen Bertenshaw, Lawrence Iben, Cathy D. Mahle, Elaine Ryan, Dedong Wu, Qi Gao, Cen Xu,