Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10598848 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
The synthesis and biological activity of novel heme oxygenase (HO) inhibitors based on the lead structure of azalanstat is presented. Potency and selectivity in the inhibition of HO-1 and HO-2 isozymes were found to be dependent on the configurational and structural features of these compounds.
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Authors
Jason Z. Vlahakis, Robert T. Kinobe, Raymond J. Bowers, James F. Brien, Kanji Nakatsu, Walter A. Szarek,