| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10599020 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
A series of potent and soluble ORL1 agonists was prepared and evaluated. Compound 41 showed antinociceptive properties in mouse formalin paw test (ED50 = 1.07 μmol/kg).
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ronald Palin, David R. Barn, John K. Clark, Jean E. Cottney, Phillip M. Cowley, Marc Crockatt, Louise Evans, Helen Feilden, Richard R. Goodwin, Frank Griekspoor, Simon J.A. Grove, Andrea K. Houghton, Philip S. Jones, Richard J. Morphy,