| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10599024 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
H-Dmt-NH-CH3 showed the highest affinity (Kiμ = 7.45 nM) equal to that of morphine, partial μ-opioid agonism (Emax = 66.6%) in vitro and a moderate antinociception in mice.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yoshio Fujita, Yuko Tsuda, Takashi Motoyama, Tingyou Li, Anna Miyazaki, Toshio Yokoi, Yusuke Sasaki, Akihiro Ambo, Hideko Niizuma, Yunden Jinsmaa, Sharon D. Bryant, Lawrence H. Lazarus, Yoshio Okada,