| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10599063 | Bioorganic & Medicinal Chemistry Letters | 2005 | 6 Pages |
Abstract
A convenient one-pot synthetic route was developed for the preparation of asymmetric 1,3-dialkyl-1,3,5-triazine-2,4,6-triones from isocyanates, primary amines and N-chlorocarbonyl isocyanate. This methodology was applied to the synthesis of a chemical library acting as antagonists of the hGnRH receptor.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhiqiang Guo, Dongpei Wu, Yun-Fei Zhu, Fabio C. Tucci, Joseph Pontillo, John Saunders, Qiu Xie, R. Scott Struthers, Chen Chen,