Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10599072 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
A series of 4-(2-pyridyl)piperazine-1-benzimidazole analogues were designed. Compound 11 was identified as a potent TRPV1 antagonist (IC50Â =Â 90Â nM, F%Â =Â 19).
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bin Shao, Jincheng Huang, Qun Sun, Kenneth J. Valenzano, Lori Schmid, Scott Nolan,