| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10599082 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
The synthesis of novel C6-aryl substituted derivatives of (S)-3-(dimethylamino)chroman is described. The novel derivatives display 5-HT7 receptor affinities that varies from nM to μM, indicating that this small set of derivatives constitute a novel and interesting starting point for further structure-serotonin 5-HT7 activity relationship (SAR) studies.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pär Holmberg, Lars Tedenborg, Susanne Rosqvist, Anette M. Johansson,