Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10599095 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
A novel class of cannabinoid CB2 receptor ligands is described. The compounds are nanomolar inhibitors of the CB2 receptor and can show high selectivity over the cannabinoid CB1 receptor. One compound is shown to be a CB2-selective inverse agonist.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Brian J. Lavey, Joseph A. Kozlowski, R. William Hipkin, Waldemar Gonsiorek, Daniel J. Lundell, John J. Piwinski, Satwant Narula, Charles A. Lunn,