| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10599100 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
A new class of benzimidazole-5-sulfonamides has been identified as nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists. Initial structure-activity relationships are presented resulting in compounds 19 and 28 with submicromolar dual functional activity on human and rat receptors.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kentaro Hashimoto, Miyuki Tatsuta, Mikayo Kataoka, Kayo Yasoshima, Yuka Shogase, Makoto Shimazaki, Takeshi Yura, Yingfu Li, Noriyuki Yamamoto, Jang B. Gupta, Klaus Urbahns,