| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10599354 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
The synthesis and SAR of a series of potent P2X7 receptor antagonists is described. The synthesis featured high-throughput solution- and solid-phase techniques including a microwave induced imidazoline formation.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gregory H. Merriman, Liang Ma, Patrick Shum, Daniel McGarry, Frank Volz, Jeffrey S. Sabol, Alexandre Gross, Zhicheng Zhao, David Rampe, Lin Wang, Friederike Wirtz-Brugger, Bruce A. Harris, Douglas Macdonald,