Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10599362 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Correolide (1) was converted to a new series of tetracyclic Kv1.3 blockers 2. SAR for this class of compounds in two functional assays, Rb_Kv and human T cell proliferation, is presented herein.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jianming Bao, Shouwu Miao, Frank Kayser, Andrew J. Kotliar, Robert K. Baker, George A. Doss, John P. Felix, Randal M. Bugianesi, Robert S. Slaughter, Gregory J. Kaczorowski, Maria L. Garcia, Sookhee N. Ha, Laurie Castonguay, Gloria C. Koo, Kashmira Shah,