Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10795848 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2012 | 8 Pages |
Abstract
⺠Heat shock causes cleavage of the cristae regulator OPA1. ⺠Heat shock causes PARL-dependent accumulation of soluble antiapoptotic OPA1. ⺠Soluble OPA1 confers secondary resistance to apoptosis to heat shocked cells. ⺠OPA1 is essential also for heat shock conditioning.
Keywords
IMSMFNFis1PARLBcl-2 associated protein XDrp1MEFsFCCPHspOMMBcl-2opa1optic atrophy 1Cytochrome c releaseimmBaxfission 1Apoptosisinner mitochondrial membraneouter mitochondrial membraneintermembrane spaceB-cell lymphoma 2mouse embryonic fibroblastsMitofusinMitochondrionHeat shock responseHeat shock proteindynamin related protein 1BAK
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Authors
Luiza K. Sanjuán Szklarz, Luca Scorrano,