Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10795853 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2012 | 4 Pages |
Abstract
⺠CO photolysis from yeast CcO induces the same carboxyl change seen in bovine CcO. ⺠E243D and I67N mutants were analysed to identify the responsible amino acid. ⺠Changes in the IR spectra definitively identify E243 as the CO-sensitive amino acid. ⺠The I67N mutation inhibits the enzyme by interfering with E243 function.
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Authors
Amandine Maréchal, Brigitte Meunier, Peter R. Rich,