Cardiolipin binding in bacterial respiratory complexes: Structural and functional implications

► Cardiolipin is a key component of energy-transducing membranes. ► Cardiolipin tunes the reactivity of the nitrate reductase complex towards quinone. ► Cardiolipin may influence quinone reactivity of the formate dehydrogenase complex. ► Polar and septal accumulation of cardiolipin is observed in bacteria. ► Cardiolipin binding may be at the origin of supercomplex formation in bacteria.