| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10795861 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2012 | 13 Pages |
Abstract
⺠20 μM Fe(II) induces mitochondrial permeability transition in isolated mitochondria. ⺠Iron causes NAD(P)H oxidation but this is only marginally involved in MPT induction. ⺠Small fraction of added iron was imported by calcium uniporter. ⺠MPT propagation continues through calcium release/reuptake. ⺠The effect of iron depends on its ability to displace calcium from residual EDTA.
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Authors
Juraj Gáll, Jan Jr., Richard Buchal, Eva SedláÄková, Karina Verébová, Jan PlátenÃk,