| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10795866 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2012 | 9 Pages |
Abstract
⺠We have reconstituted functional Respiratory Complex II into phospholipid nanodiscs. ⺠Cardiolipin is essential for the stability and enzymatic activity of Complex II. ⺠The presence of cardiolipin curtails the production of superoxide by Complex II.
Keywords
DDMNanodiscdecylubiquinoneDCPIPPoPCMSPOXPHOSdMPC1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine1,2-dimyristoyl-sn-glycero-3-phosphocholinedodecyl-β-D-maltosideEDTAEthylenediaminetetraacetic aciddichlorophenolindophenolinner membranephosphatidylcholinephosphatidylglycerolphosphatidylethanolamineOxidative phosphorylationPOPECardiolipin
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Authors
Christine T. Schwall, Victoria L. Greenwood, Nathan N. Alder,