Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10795888 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2012 | 11 Pages |
Abstract
⺠Kinetic-master equations model proton pumping in cytochrome c oxidase. ⺠Proton pumping at low efficiency can be achieved without kinetic gating. ⺠High thermodynamic efficiency of pumping requires kinetic gating. ⺠Internal proton transfer to pump site is key gated reaction step. ⺠Glu valve at the end of the D channel increases the pumping efficiency.
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Authors
Young C. Kim, Gerhard Hummer,