Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10795900 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2012 | 8 Pages |
Abstract
⺠OXPHOS allowscells to produce more ATP but also toxic elements such as ROS and NADH. ⺠Success of endosymbiosis has depended on the regulation of endosymbiont OXPHOS. ⺠Cytochrome c oxidase (COX) is a key regulator of OXPHOS. ⺠Addition of nuclear subunits controlling mitochondrial subunits marks COX evolution. ⺠COX control function is an as yet under-appreciated key point of evolution.
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Authors
Denis Pierron, Derek E. Wildman, Maik Hüttemann, Gopi Chand Markondapatnaikuni, Siddhesh Aras, Lawrence I. Grossman,