Article ID Journal Published Year Pages File Type
10795900 Biochimica et Biophysica Acta (BBA) - Bioenergetics 2012 8 Pages PDF
Abstract
► OXPHOS allowscells to produce more ATP but also toxic elements such as ROS and NADH. ► Success of endosymbiosis has depended on the regulation of endosymbiont OXPHOS. ► Cytochrome c oxidase (COX) is a key regulator of OXPHOS. ► Addition of nuclear subunits controlling mitochondrial subunits marks COX evolution. ► COX control function is an as yet under-appreciated key point of evolution.
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