Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10824203 | Insect Biochemistry and Molecular Biology | 2012 | 9 Pages |
Abstract
⺠We characterized a midgut-specific chitin synthase gene (LmCHS2) from Locusta migratoria. ⺠LmCHS2 was mainly expressed in apical regions of brush border forming columnar cells of gastric caeca. ⺠RNAi of LmCHS2 led to a feeding cessation and high mortality of the insect. ⺠RNAi effect attributed to a reduced synthesis of chitin and disruption of peritrophic matrix (PM) formation. ⺠LmCHS2 is responsible for the biosynthesis of chitin associated with PM and plays an essential role in locust growth and development.
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Authors
Xiaojian Liu, Huanhuan Zhang, Sheng Li, Kun Yan Zhu, Enbo Ma, Jianzhen Zhang,