| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10837444 | Pesticide Biochemistry and Physiology | 2013 | 7 Pages |
Abstract
- Activity-guided fractionation of Brucea javanica led to the isolation of brusatol.
- The structure of brusatol was identified by crystallographic analysis.
- Brusatol has potent insecticidal activities against larvae of Spodoptera exigua.
- Brusatol demonstrated cytotoxic effects to the tested insect cell lines.
- Brusatol induced apoptosis involved caspase-3 activation and cytochrome c release.
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Authors
Lan Zhang, Xuehuan Feng, Dejun Ma, Jingjing Yang, Hongyun Jiang, Yanning Zhang, Weizhi He,