| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10869346 | Current Opinion in Plant Biology | 2005 | 5 Pages |
Abstract
TILLING (Targeting Induced Local Lesions IN Genomes) is a powerful reverse genetic technique that employs a mismatch-specific endonuclease to detect induced or natural DNA polymorphisms. Its advantages over other reverse genetic techniques include its applicability to virtually any organism, its facility for high-throughput and its independence of genome size, reproductive system or generation time. TILLING is currently being used for the detection of both induced and natural variation in several plant species.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Plant Science
Authors
Erin J Gilchrist, George W Haughn,