Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10870564 | FEBS Letters | 2014 | 6 Pages |
Abstract
Rice OsHMA3 is a vacuolar cadmium (Cd) transporter belonging to the P1B-ATPase family and has a long (273aa) C-terminal region. We analyzed the function of the region related to Cd using the transgenic Arabidopsis Col-0 ecotype, which is sensitive to Cd. The OsHMA3 variant containing a truncated (58aa) C-terminal region did not confer Cd tolerance, whereas an OsHMA3 variant containing a longer truncated (105aa) C-terminal region conferred Cd tolerance to transgenic Arabidopsis. We conclude that the C-terminal region, particularly the region containing the first 105aa, has an important role in OsHMA3 activity.
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Authors
Saori Kumagai, Tatsuya Suzuki, Kouichi Tezuka, Namiko Satoh-Nagasawa, Hidekazu Takahashi, Kenji Sakurai, Akio Watanabe, Tatsuhito Fujimura, Hiromori Akagi,