| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10870934 | FEBS Letters | 2013 | 8 Pages |
Abstract
⺠hZFP57 zinc finger 3 and 4 are sufficient for high affinity DNA binding. ⺠hZFP57 TNDM1 mutations (R248H and H277N) affect DNA binding. ⺠DNA sequences in the TNDM1 ICR show DNA methylation-dependent binding to hZFP57. ⺠mZfp57 inactivation results in loss of DNA promoter methylation and Plagl1 activation.
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Authors
Ilaria Baglivo, Sabrina Esposito, Lucia De Cesare, Angela Sparago, Zahra Anvar, Vincenzo Riso, Marco Cammisa, Roberto Fattorusso, Giovanna Grimaldi, Andrea Riccio, Paolo V. Pedone,