Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10870953 | FEBS Letters | 2013 | 6 Pages |
Abstract
⺠Engrailed (En) is a member of the homeobox gene family. ⺠En encodes a transcription factor that is essential during early development. ⺠The only known site of normal adult EN protein expression is in the nervous system. ⺠Over-expression of EN has been linked to breast, prostate and ovarian cancers. ⺠EN2 may prove useful as a biomarker, notably in the urine of prostate cancer patients.
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Authors
Sophie E. McGrath, Agnieszka Michael, Hardev Pandha, Richard Morgan,